Recognition of human milk oligosaccharides by bacterial exotoxins
نویسندگان
چکیده
منابع مشابه
Oligosaccharides of Human Milk
Two new octasaccharides were isolated from human milk of a nonsecretor Lewis a+bindividual. Structural studies by sequential enzymic degradation and by quantitative methylation analysis revealed that their structures were as follows: Gal/31 + 3 (Fuccul + 4) GlcNAcPl + 3Gal/H -+ 4 (Fucal -+ 3) GlcNAcPl + 3Gal/31+ 4Glc, Gal/?1 + 4 (Fuccul -+ 3) GlcNAcj31 + 3Gal/31 -+ 4 (Fuccul -+ 3) GlcNAcj31 + 3...
متن کامل5410 Oligosaccharides of Human Milk
Two new octasaccharides were isolated from human milk of a nonsecretor Lewis a+bindividual. Structural studies by sequential enzymic degradation and by quantitative methylation analysis revealed that their structures were as follows: Gal/31 + 3 (Fuccul + 4) GlcNAcPl + 3Gal/H -+ 4 (Fucal -+ 3) GlcNAcPl + 3Gal/31+ 4Glc, Gal/?1 + 4 (Fuccul -+ 3) GlcNAcj31 + 3Gal/31 -+ 4 (Fuccul -+ 3) GlcNAcj31 + 3...
متن کاملMethods for the quantitation of human milk oligosaccharides in bacterial fermentation by mass spectrometry.
Oligosaccharides are the third most abundant component in human milk. In the past decades, it became apparent that they would be able to protect against pathogens and participate in the development of the gut microflora for infants. However, their role in infants' nutrition and development remains poorly understood. To better understand this function, it is extremely important to have a quantit...
متن کاملConsumption of human milk oligosaccharides by gut-related microbes.
Human milk contains large amounts of complex oligosaccharides that putatively modulate the intestinal microbiota of breast-fed infants by acting as decoy binding sites for pathogens and as prebiotics for enrichment of beneficial bacteria. Several bifidobacterial species have been shown to grow well on human milk oligosaccharides. However, few data exist on other bacterial species. This work exa...
متن کاملRegulatory Aspects of Human Milk Oligosaccharides.
Human milk oligosaccharides are key components of human milk and appear in various compositions and concentrations in all human milks. In regulatory sense human milk oligosaccharides are classified as novel foods or novel food ingredients requiring safety assessment. In addition, if any health messages are intended to be used also health claim regulations apply. This chapter reviews the regulat...
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ژورنال
عنوان ژورنال: Glycobiology
سال: 2015
ISSN: 0959-6658,1460-2423
DOI: 10.1093/glycob/cwv025